I run full synthetic in everything I own, including a 360fe block, and my 460 which is a 96 so its had the benefit of more modern tooling in its making, and tighter clearances as witnessed by the 10w30 weight oil its speked to have vs 10w40 oil from years past. The fe block has been in the family since 75, and is a 73 model year. 101k on the clock and I highly doubt it will go another 100k even with the Mobil 1 oil that's been used in it as long as I've been driving. Theres been more then a few instances of cams being wiped out from the lower ZDDP additives in modern oils, mainly from the cams not being as hard as modern cams metal. Would they have lasted longer? Likely but I doubt any of them would be hitting the 300k mark even with the best oil on the planet. But hey, I'm just another idiot on the internet, and we just started another oil debate.