As far as the carb, you need to be able to put at least 9:1 in for E100 and 6:1 for meth as oposed to 14:1 for gas. Also alcohol if I am not mistaken likes to be on the rich side of stoiometric for max HP. Pump Gas produces max exhaust pressure at about 20% rich, alcohol is more like 40%.
As far as the carb mod the diamiter of the orffices will need to be effectivly opened by ~30% for ethyl or ~40% for meth. to accomdate the increased fuel requirment, the fuel viscosity also plays a factor in this, as the viscosity and density of pump gas and alcohol. That is the weight of alcohol or pump gas that will flow through a given carb opening at a given pressure is not the same.